| First Round | Team | Pick |
| 1 | Tigers | Casey Mize, RHP, Auburn |
| 2 | Giants | Joey Bart, C, Georgia Tech |
| 3 | Phillies | Nick Madrigal, MIF, Oregon State |
| 4 | White Sox | Matt Liberatore, LHP, Mountain Ridge HS (AZ) |
| 5 | Reds | Alec Bohm, 1B, Wichita State |
| 6 | Mets | Brady Singer, RHP, Florida |
| 7 | Padres | Carter Stewart, RHP, Eau Gallie HS (FL) |
| 8 | Braves | Jonathan India, 3B, Florida |
| 9 | A’s | Cole Winn, RHP, Orange HS (CA) |
| 10 | Pirates | Nolan Gorman, 3B, Sandra Day O’Connor HS (AZ) |
| 11 | Orioles | Jared Kelenic, Waukesha West HS (WI) |
| 12 | Blue Jays | Trevor Larnach, OF, Oregon State |
| 13 | Marlins | Travis Swaggerty, OF, South Alabama |
| 14 | Mariners | Jackson Kowar, RHP, Florida |
| 15 | Rangers | Ryan Weathers, LHP, Loretto HS (TN) |
| 16 | Rays | Ryan Rolison, LHP, Ole Miss |
| 17 | Angels | Shane McClanahan, LHP, South Florida |
| 18 | Royals | Ethan Hankins, RHP, Forsyth Central HS (GA) |
| 19 | Cardinals | Connor Scott, OF, Plant HS (FL) |
| 20 | Twins | Logan Gilbert, RHP, Stetson |
| 21 | Brewers | Seth Beer, 1B/OF, Clemson |
| 22 | Rockies | Grayson Rodriguez, RHP, Central Heights HS (TX) |
| 23 | Yankees | Brice Turang, SS, Santiago HS (CA) |
| 24 | Cubs | Kumar Rocker, RHP, North Oconee HS (GA) |
| 25 | D-backs | Noah Naylor, C, St. Joan of Arc Catholic HS (CAN) |
| 26 | Red Sox | Tristan Casas, 1B, American Heritage HS (FL) |
| 27 | Nationals | Mason Denaburg, RHP, Merritt Island HS (FL) |
| 28 | Astros | Jake McCarthy, OF, Virginia |
| 29 | Indians | Cole Wilcox, RHP, Heritage HS (GA) |
| 30 | Dodgers | Jeremy Eierman, SS, Missouri State |
| Supplemental First Round | ||
| 31 | Rays | Steele Walker, OF, Oklahoma |
| 32 | Rays | Anthony Siegler, C, Cartersville HS (GA) |
| 33 | Royals | Nico Hoerner, SS, Stanford |
| 34 | Royals | Tristan Beck, RHP, Stanford |
| 35 | Indians | Jameson Hannah, OF, Dallas Baptist |
| Competitive Balance A | ||
| 36 | Pirates | J.T. Ginn, RHP, Brandon HS (MS) |
| 37 | Orioles | Adam Kloffenstein, RHP, Magnolia HS (TX) |
| 38 | Padres | Parker Meadows, OF, Grayson HS (GA) |
| 39 | D-backs | Nick Schnell, OF, Roncalli HS (IN) |
| 40 | Royals | Jordyn Adams, OF, Green Hope HS (NC) |
| 41 | Indians | Kris Bubic, LHP, Stanford |
| 42 | Rockies | Kyler Murray, OF, Oklahoma |
| 43 | Cardinals | Jordan Groshans, SS/3B, Magnolia HS (TX) |
| Second Round | ||
| 44 | Tigers | Xavier Edwards, SS, North Broward Prep (FL) |
| 45 | Giants | Blaine Knight, RHP, Arkansas |
| 46 | White Sox | Lenny Torres Jr., Beacon HS (NY) |
| 47 | Reds | Sean Hjelle, RHP, Kentucky |
| 48 | Mets | Alek Thomas, OF, Mt. Carmel HS (IL) |
| 49 | Braves | Jeremiah Jackson, SS, St. Lukes (AL) |
| 50 | A’s | Greyson Jenista, OF/1B, Wichita State |
| 51 | Pirates | Cadyn Grenier, SS, Oregon State |
| 52 | Blue Jays | Will Banfield, C, Brookwood HS (GA) |
| 53 | Marlins | Mike Siani, OF, William Pen Charter (PA) |
| 54 | Mariners | Daniel Lynch, LHP, Virginia |
| 55 | Rangers | Aaron Hernandez, RHP, Texas A&M – Corpus Christi |
| 56 | Rays | Gunnar Hoglund, RHP, Fivay HS (NC) |
| 57 | Angels | Konnor Pilkington, LHP, Mississippi State |
| 58 | Royals | Matt McClain, MIF, Beckam HS (CA) |
| 59 | Twins | Kyle Isbel, OF, UNLV |
| 60 | Brewers | Jonathan Ornelas, SS, Kellis HS (AZ) |
| 61 | Yankees | Griffin Conine, OF, Duke |
| 62 | Cubs | Grant Little, SS, Texas Tech |
| 63 | D-backs | Colton Eastman, RHP, Cal State Fullerton |
| 64 | Red Sox | Owen White, RHP, Jesse C. Carson HS (NC) |
| 65 | Nationals | Durbin Feltman, RHP, TCU |
| 66 | Astros | Trey Riley, RHP, Logan (IL) JC |
| 67 | Indians | Griffin Roberts, RHP, Wake Forest |
| 68 | Dodgers | Joe Gray Jr., OF, Hattiesburg HS (MS) |
| Competitive Balance B | ||
| 69 | Marlins | Nick Decker, OF, Seneca HS (NJ) |
| 70 | A’s | Tyler Frank, MIF, Florida Atlantic |
| 71 | Rays | Zach Watson, OF, LSU |
| 72 | Reds | Cole Sands, RHP, Florida State |
| 73 | Brewers | Ryder Green, OF, Karns HS (TN) |
| 74 | Padres | Tim Cate, LHP, Uconn |
| Supplemental Second Round | ||
| 75 | Cardinals | Terrin Vavra, SS, Minnesota |
| 76 | Rockies | Cal Raleigh, C, Florida State |
| 77 | Cubs | Osiris Johnson, SS, Encinal HS (GA) |
| 78 | Cubs | Zack Hess, RHP, LSU |
The Stain Sports 